Prescription only · clinician reviewed
KLOW — GHK-Cu, BPC-157, TB-500, and KPV
A four-peptide blend studied for how the body repairs, recovers, and renews skin.
Member pricing via Renovatti Wellness
- One charge for this supply
- Clinician review and care-team messaging included
- Pay once for this supply. No automatic renewal — start a new consult if you want more later.
- This is not a subscription. There is nothing to cancel.
Free eligibility check · $0 today · You are charged only if a clinician prescribes
Shipping and clinician visit added at checkout.
Choosing a plan starts an intake, not an order. A licensed clinician reviews it and decides whether to prescribe — they may decline, and you are not charged unless they approve.
KLOW — GHK-Cu, BPC-157, TB-500, and KPV
A four-peptide blend studied for how the body repairs, recovers, and renews skin.
- Tissue repair
- Systemic recovery
- Inflammatory balance
Why people ask about it
What this is for
Tissue repair
BPC-157 and GHK-Cu have been studied for their role in repairing tendon, gut lining, and skin in laboratory and animal models.
Systemic recovery
TB-500 comes from thymosin beta-4, which helped cells migrate into damaged tissue in wound-healing research.
Inflammatory balance
KPV has been studied for calming inflammatory signalling, mostly in models of gut inflammation.
Individual results vary. Your clinician decides whether it is right for you.
Before you start
What to know about KLOW
KLOW combines BPC-157, TB-500, GHK-Cu, and KPV in one compounded vial, so there is one prescription instead of four. A licensed clinician reviews your intake by message and decides whether it fits you.
- 01
KLOW combines four peptides, BPC-157, TB-500, GHK-Cu, and KPV, in one vial.
- 02
Each one is studied on a different repair pathway: gut and tendon, cell migration, collagen, and inflammatory signalling.
- 03
Almost all of the evidence comes from cell and animal studies. No trial has tested this blend in people.
- 04
It ships as a freeze-dried powder that is mixed before use.
- 05
Supplied as a compounded medication, which means it is not FDA-approved.
Who this tends to fit
- You want one vial instead of several separate peptides
- You are interested in recovery, connective tissue, gut, or skin support
- You are comfortable mixing a powder vial before use
- You want a clinician to review it first
Fitting the description does not mean you will be prescribed this. A clinician decides after reviewing your intake.
KLOW is a compounded blend, so it is not FDA-approved and the FDA has not reviewed it for safety, effectiveness, or quality. Almost all of the research on these peptides is in cells and animals, and none of it tested this combination in people. The FDA has flagged limited human safety data for several of these peptides. It is not a treatment for any disease or injury.
The science
The science of KLOW
Tap a card to see the research behind each pathway.
How care works
What clinician oversight means here
Licensed clinicians, real review, and support after you start.
A licensed clinician decides
Your intake is reviewed by a clinician licensed in your state. They choose the treatment and the dose, and they can decline. Insert MD does not make that call.
Dispensed by a licensed pharmacy
Nothing ships without a prescription. Your order is prepared and sent by a licensed pharmacy, not packed by us.
Reviewed again at follow-up
Continuing is a decision, not a default. Your clinician reassesses whether the treatment still fits before you carry on.
Compounded is not FDA-approved
Several treatments here are compounded. The FDA does not review compounded medications for safety, effectiveness, or quality, and we say so on every page where it applies.
How it works
Three steps, no charge to find out
Check eligibility
A quick questionnaire — takes about 2 minutes. No charge to see if you qualify.
Provider review
A licensed clinician reviews your intake and approves an appropriate plan.
Delivered to you
Your treatment ships directly to your door, with care-team support.
Precise, consistent dosing
Your prescription is prepared by a licensed pharmacy and reviewed by a clinician licensed in your state. Nothing ships until they approve.
- Compounded by a licensed pharmacy
- Dose set by a licensed clinician
- Ships as a powder with mixing directions from the pharmacy
Good to know
Each peptide is studied on a different pathway. BPC-157 has been studied in gut and tendon repair models. TB-500 is a short fragment of thymosin beta-4, a protein that helps cells move to where repair is needed. GHK-Cu is a copper peptide linked to collagen production. KPV is a three-amino-acid fragment of alpha-MSH studied for inflammatory signalling in the gut. Most of this work is in cells and animals.
KLOW is a compounded blend, so it is not FDA-approved and the FDA has not reviewed it for safety, effectiveness, or quality. Almost all of the research on these peptides is in cells and animals, and none of it tested this combination in people. The FDA has flagged limited human safety data for several of these peptides. It is not a treatment for any disease or injury.
One freeze-dried vial holds 50 mg GHK-Cu and 10 mg each of BPC-157, TB-500, and KPV. The pharmacy label lists each amount.
No. KLOW ships as a powder that is mixed before use. Follow the pharmacy's directions that come with your order, and message your clinician with any questions.
It is priced as about a 30-day supply at a typical prescribed dose. Your clinician's dose decides how long it actually lasts.
References
Scientific sources
The primary papers, for readers who want to go deeper.
- 1.Sikiric P, Seiwerth S, Rucman R, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17(16):1612-32.
- 2.Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011;110(3):774-80.
- 3.Goldstein AL, Hannappel E, Sosne G, Kleinman HK. Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51.
- 4.Malinda KM, Sidhu GS, Mani H, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364-8.
- 5.Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, Yan Y, Sitaraman S, Merlin D. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. 2008;134(1):166-78.
- 6.Kannengiesser K, Maaser C, Heidemann J, et al. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflamm Bowel Dis. 2008;14(3):324-31.
- 7.Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Lett. 1988;238(2):343-6.
- 8.Pickart L, Margolina A. Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. Int J Mol Sci. 2018;19(7):1987.
Plain language
Terms you might hear
- Peptide
- A short chain of amino acids. Most act as signals between cells.
- Lyophilized
- Freeze-dried into a powder so the peptide stays stable in shipping. It is mixed with a sterile liquid before use.
- Thymosin beta-4
- A protein found in most cells that helps control actin, the filament cells use to move. TB-500 is a fragment of it.
- Collagen
- The structural protein that gives skin, tendon, and connective tissue their strength.
- Fibroblast
- The cell in skin and connective tissue that produces collagen and other matrix proteins.
- Compounded
- Prepared for an individual patient by a licensed pharmacy. Compounded medications are not FDA-approved.
Ready when you are
See if KLOW is right for you
A licensed clinician reviews your intake and decides. You are not charged unless they approve.
KLOW — GHK-Cu, BPC-157, TB-500, and KPV
$150.00 · $0 today